Substance P Rat Monoclonal Antibody (NC1/34) | FR | MédiMabs

Substance P Rat Monoclonal Antibody (NC1/34)

Substance P Rat Monoclonal Antibody (NC1/34)

Substance P Rat Monoclonal Antibody (NC1/34)

MM-0001-1 -- anti-Substance P
$355,00/0.5 mL
QTY
Pour les prix de gros, nous contacter.
NUMÉRO : MM-0001-1
  • Nom du produit
    Substance P Rat Monoclonal Antibody (NC1/34)
  • Serveur
    Rat
  • Clonality
    Monoclonal
  • Tested Applications
    IHC,ICC
  • Research Area(s)
    Neuroscience, Cancer, Metabolism
  • Immunogen
    Substance P
  • Modifications
    None
  • Clone ID
    NC1/34
  • DataSHEET
  • Isotype
    IgG2a
  • Conjugation
    None
  • Reactivity
    This antibody recognizes the COOH-terminal end of substance P. It does not recognize Leu- or Met enkephalin, somatostatin or beta-endorphin; cross-reactivity with eledoisin: 5%. It recognizes Substance P in postmortem tissue of the human brain.
  • Specificity
    predicted to all mammalian species, crab and pigeon
  • Purification
    Non Purified
  • Target Name
    Substance P
  • Storage Buffer
    Tissue culture supernatant
  • Alias
    anti-Substance P, tachykinin, neuropeptide, neurokinin, SP, anti-tachykinin, anti-neuropeptide, anti-neurokinin, anti-SP
  • Format
    0.5 mL
  • Background
    The discovery of substance P (SP) was reported in 1931. After more than 70 years of investigation, SP is perhaps the best understood neuropeptide transmitter. Substance P is an undecapeptide, which by the mid-1980s was recognized to belong to the tachykinin peptide family; it is also member of the neurokinins. It has been proposed that SP, released from primary afferent nerve endings, plays a role in chronic inflammation and pain. Neurotransmitters appear to play a key role in the regulation of emotions and antagonists of their receptors may be novel psychotropic drugs of the future.

For laboratory research only, not for drug, diagnostic or other use.

  • Alleviating Pain Hypersensitivity through Activation of Type 4 Metabotropic Glutamate Receptor
  • De Novo Expression of Neurokinin-1 Receptors by Spinoparabrachial Lamina I Pyramidal Neurons Following a Peripheral Nerve Lesion
  • De Novo Expression of the Neurokinin 1 Receptor in Spinal Lamina I Pyramidal Neurons in Polyarthritis
  • Parasympathetic nerve fibers invade the upper dermis following sensory denervation of the rat lower lip skin
  • Skin blood vessels are simultaneously innervated by sensory, sympathetic and parasympathetic fibers
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