Hyphen D12 Rabbit Polyclonal Antibody | FR | MédiMabs

Hyphen D12 Rabbit Polyclonal Antibody

Hyphen D12 Rabbit Polyclonal Antibody

  • Hyphen D12 Rabbit Polyclonal Antibody
  • Hyphen D12 Rabbit Polyclonal Antibody
  • Hyphen D12 Rabbit Polyclonal Antibody

Hyphen D12 Rabbit Polyclonal Antibody

MM-0227 -- anti-Hyphen D12
$355,00/100 µl
QTY
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NUMÉRO : MM-0227
  • Nom du produit
    Hyphen D12 Rabbit Polyclonal Antibody
  • Serveur
    Rabbit
  • Clonality
    Polyclonal
  • Tested Applications
    WB
  • DataSHEET
  • Conjugation
    None
  • Reactivity
    Human, mouse
  • Specificity
    Full length
  • Purification
    Non Puriifed
  • Target Name
    SamD12
  • Format
    100 µl
  • Background
    SamD10 and SamD12 are two recently discovered homolog proteins consisting of a SAM domain. These proteins are also know as Hyphen (HYP) or Aveugle (Ave) and they have been demonstrated to interact with the SAM domain of the Connector enhancer of KSR (CNK) downstream of RAS but a step upstream of RAF. A role for these proteins downstream of EGFR during eye and wing development of Drosophila has also been demonstrated. Heterodimerization of CNK/SAM has been shown to facilitate the recruitment of a KSR/MEK complex to CNK and bridge KSR/MEK to RAF which greatly enhances RAS-mediated RAF activation.

For laboratory research only, not for drug, diagnostic or other use.

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