Anti-Nerve Growth Factor (NGF) Rat Monoclonal Antibody - Purified | FR | MédiMabs

Anti-Nerve Growth Factor (NGF) Rat Monoclonal Antibody - Purified

Anti-Nerve Growth Factor (NGF) Rat Monoclonal Antibody - Purified

Anti-Nerve Growth Factor (NGF) Rat Monoclonal Antibody - Purified

MM-0009-P -- Purified anti-Nerve growth Factor (NGF)
$482,00/100 µl
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NUMÉRO : MM-0009-P
  • Nom du produit
    Anti-Nerve Growth Factor (NGF) Rat Monoclonal Antibody - Purified
  • Serveur
  • Clonality
  • Tested Applications
    Western blot (WB), Immunofluorescence (IF), ELISA (E)
  • Research Area(s)
  • Immunogen
    Polymerized NGF
  • Modifications
  • Clone ID
  • DataSHEET
  • Isotype
  • Conjugation
  • Reactivity
    This antibody recognizes mouse NGF monomer protein (MW 13 kDa) by WB. It does not cross react with EGF, BSA, APO or insulin
  • Specificity
    mouse; other species not tested
  • Purification
    Protein G
  • Target Name
    Nerve growth Factor
  • Storage Buffer
  • Alias
    Beta-nerve growth factor, Beta-NGF, NGF
  • Format
    100 µl
  • Background
    Nerve growth factor (NGF) is a small secreted protein which induces the differentiation and survival of particular target neurons. It is perhaps the prototypical growth factor, in that it is one of the first to be described. NGF is critical for the survival and maintenance of sympathetic and sensory neurons. NGF is released from the target cells, binds to and activates its high affinity receptor (TrkA), and is internalized into the responsive neuron. There is some data that shows that NGF can be transported from the axon tip to soma. One of the most important molecules in the nervous system, nerve growth factor and its other neurotrophin family members control the development of the nervous system in the embryo and the maintenance of nervous tissue and neural transmission in the adult.

For laboratory research only, not for drug, diagnostic or other use.

  • A nerve growth factor mimetic TrkA antagonist causes withdrawal of cortical cholinergic boutons in the adult rat.
  • A TrkA-selective, fast internalizing nerve growth factor-antibody complex induces trophic but not neuritogenic signals
  • Two distinct monoclonal antibodies raised against mouse beta nerve growth factor. Generation of bi-specific anti-nerve growth factor anti-horseradish peroxidase antibodies for use in a homogeneous enzyme immunoassay
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