Munc13-4 Rabbit Polyclonal Antibody | FR | MédiMabs

Munc13-4 Rabbit Polyclonal Antibody

Munc13-4 Rabbit Polyclonal Antibody

Munc13-4 Rabbit Polyclonal Antibody

MM-0130 -- anti-Munc13-4
$355,00/50 µl
QTY
Pour les prix de gros, nous contacter.
NUMÉRO : MM-0130
  • Nom du produit
    Munc13-4 Rabbit Polyclonal Antibody
  • Serveur
    Rabbit
  • Clonality
    Polyclonal
  • Tested Applications
    WB,IP
  • DataSHEET
  • Conjugation
    None
  • Reactivity
    Human
  • Specificity
    N-terminal
  • Purification
    Non Purified
  • Target Name
    Munc13-4
  • Alias
    anti-Munc13-4
  • Format
    50 µl
  • Background
    Protein unc-13 homolog D (Munc13-4) is involved in cytotoxic granule exocytosis in lymphocytes. It regulates assembly of recycling and late endosomal structures which leads to the formation of an endosomal exocytic compartment. It also regulates Ca 2+-dependent secretory lysosome exocytosis in mast cells. Munc13- 4 is highly expressed in the spleen, thymus and leukocytes and to a lesser extent in the lung and placenta, brain, heart, skeletal muscle and kidney. Defects in Munc13-4 are the cause of hemophagocytic lymphohistiocytosis familial type 3 (FHL3).

For laboratory research only, not for drug, diagnostic or other use.

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