HHV-6 Variant A IE2 Protein Mouse Monoclonal Antibody | FR | MédiMabs

HHV-6 Variant A IE2 Protein Mouse Monoclonal Antibody

HHV-6 Variant A IE2 Protein Mouse Monoclonal Antibody

HHV-6 Variant A IE2 Protein Mouse Monoclonal Antibody

MM-0071 -- anti-HHV-6 Variant A IE2 Protein
$355,00/200 µl
QTY
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NUMÉRO : MM-0071
  • Nom du produit
    HHV-6 Variant A IE2 Protein Mouse Monoclonal Antibody
  • Serveur
    Mouse
  • Clonality
    Monoclonal
  • Tested Applications
    Western blot (WB), Immunofluorescence (IF), ELISA (E)
  • Research Area(s)
    Microbiology
  • Immunogen
    Full length IE2
  • Modifications
    None
  • Clone ID
    P6H8
  • DataSHEET
  • Isotype
    IgG1
  • Conjugation
    None
  • Reactivity
    The antibody recognizes the extracellular epitope of the protein IE2 (aa 1078-1089)
  • Specificity
    variant A of HHV-6 and does not cross-react with the IE2 protein from variant B
  • Purification
    Non Purified
  • Target Name
    HHV6 Immediate-early protein 2
  • Storage Buffer
    Protein free tissue culture supernatant
  • Alias
    Immediate-early protein 2, U90/U87/U86, BCLF0
  • Format
    200 µl
  • Background
    HHV-6 is a double stranded DNA virus belonging to the betaherpesvirinae subfamily. HHV-6 viruses comprise two distinct species: HHV-6A and HHV-6B. HHV-6 is a T-cell lymphotropic virus with high affinity for CD4 lymphocytes and is capable of infecting virtually all human beings. HHV-6B is responsible for at least 97% of HHV-6 infections in the USA while HHV-6A is frequently associated with patients with neuroinflammatory diseases such as multiple sclerosis. HHV-6A and HHV-6B proteins share more than 92% of their amino acids composition. However, the immediate-early protein locus A, has less than 70% of homology between the two species. At this locus, IE1 and IE2 proteins are encoded with IE2 being the most divergent between HHV-6A and HHV-6B. IE2 is expressed within few hours’ post-infection and is a potent transactivator of multiple cellular and viral promoters.

For laboratory research only, not for drug, diagnostic or other use.

  • Epitope mapping of a monoclonal antibody specific for human herpesvirus 6 variant A immediate-early 2 protein
  • Generation and characterization of a monoclonal antibody specific for human herpesvirus 6 variant A immediate-early 2 protein
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