Leu-enkephalinMouse Monoclonal Antibody | FR | MédiMabs

Leu-enkephalinMouse Monoclonal Antibody

Leu-enkephalinMouse Monoclonal Antibody

Leu-enkephalinMouse Monoclonal Antibody

MM-0006 -- anti-Leu-enkephalin
$355,00/200 µl
QTY
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NUMÉRO : MM-0006
  • Nom du produit
    Leu-enkephalinMouse Monoclonal Antibody
  • Serveur
    Mouse
  • Clonality
    Monoclonal
  • Tested Applications
    Immunohistochemistry (IHC), electron microscopy immunocytochemistry (ICC), Radioimmunoassay (RIA)
  • Research Area(s)
    Neuroscience, Signal Transduction, Immunology
  • Immunogen
    pentapeptide (Tyr-Gly-Gly-Phe-Leu)
  • Modifications
    None
  • Clone ID
    NOC1
  • DataSHEET
  • Isotype
    IgG1
  • Conjugation
    None
  • Reactivity
    This antibody does not distinguish between Met5-enkephalin and Leu5-enkephalin by radioimmunoassay or by immunocytochemistry. It is recommended for localizing enkephalinergic sites by immunohistochemistry. It does not bind to beta-endorphin or dynorphin-
  • Specificity
    Rat and Human
  • Purification
    Non Purified
  • Target Name
    Leu-enkehalin
  • Storage Buffer
    Tissue culture supernatant
  • Alias
    Enkephalin, endorphins, endorphin, Met5-enkephalin, Leu5-enkephalin, Met-enkephalin, Leu-enkephalin, anti-Enkephalin, anti-endorphins, anti-endorphin, anti-Met5-enkephalin, anti-Leu5-enkephalin, anti-Met-enkephalin, anti-Leu-enkephalin
  • Format
    200 µl
  • Background
    Enkephalins (penta-peptides) have been discovered as regulators of nerve impulses involving pain in the brain. It has been shown that these peptides act as natural analgesics (pain-killers) and their action mimics that of morphine and other opiates. At present, it is thought that the morphine-like effects are due to aromatic side chains on phenylanine and tyrosine which mimic a similar structure on morphine. Research shows that it does not make much difference whether the enkephalin contains methionine or leucine at the acid end of the peptide for its action.

For laboratory research only, not for drug, diagnostic or other use.

  • Cholinergic interneurons are differentially distributed in the human striatum
  • Ultrastructural localization of enkephalin and mu-opioid receptors in the rat ventral tegmental area
  • Substance P and enkephalin immunoreactivities in axonal boutons presynaptic to physiologically identified dorsal horn neurons. An ultrastructural multiple-labelling study in the cat
  • Mimics of the binding sites of opioid receptors obtained by molecular imprinting of enkephalin and morphine
  • Characterization and immunocytochemical application of monoclonal antibodies against enkephalins
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