Small glutamine-rich tetratricopeptide repeat (SGT) containing protein Mouse Monoclonal Antibody (6A4) - Purified | MédiMabs

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Small glutamine-rich tetratricopeptide repeat (SGT) containing protein Mouse Monoclonal Antibody (6A4) - Purified

Small glutamine-rich tetratricopeptide repeat (SGT) containing protein Mouse Monoclonal Antibody (6A4) - Purified

Small glutamine-rich tetratricopeptide repeat (SGT) containing protein Mouse Monoclonal Antibody (6A4) - Purified

MM-0214-P -- anti-SGT repeat containing protein
$482.00/100 µg
QTY
For bulk pricing, please contact us.
Catalog Number : MM-0214-P
  • Product Name
    Small glutamine-rich tetratricopeptide repeat (SGT) containing protein Mouse Monoclonal Antibody (6A4) - Purified
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Clone ID
    6A4
  • DataSHEET
  • Isotype
    IgG1
  • Conjugation
    None
  • Reactivity
    Mouse
  • Specificity
    Full length
  • Purification
    Purified
  • Format
    100 µg
  • Background
    The SGT/UBP protein (also known as small glutamine-rich tetratricopeptide repeat (TPR)- containing protein A, Alpha-SGT, Vpu-Binding Protein, UBP, SGTA, SGT or SGT1) is a ubiquitously expressed cochaperone protein which contains three TPR protein-protein interaction repeats. SGT/UBP binds to Hsp70, negatively affecting its function. SGT/UBP interacts with the Viral protein U (Vpu) and Group specific Antigen (Gag) proteins from HIV-1 and with the nonstructural protein NS-1 of parvovirus H-1; the protein/chaperone complex is thought to be involved in Vpu function and HIV particle exit and in parvovirus DNA replication. SGT/UBP also interacts with SARS-CoV Accessory Protein 7a, although the function remains unknown. Furthermore, SGT/UBP is believed to be a component of the androgen receptor (AR)-chaperone-co-chaperone complex, acting as a co-chaperone involved in androgen signaling.

For laboratory research only, not for drug, diagnostic or other use.

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