HRS Mouse Monoclonal Antibody - Purified | MédiMabs

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HRS Mouse Monoclonal Antibody - Purified

HRS Mouse Monoclonal Antibody - Purified

  • HRS Mouse Monoclonal Antibody - Purified

HRS Mouse Monoclonal Antibody - Purified

MM-0061-P -- anti-Hrs
$333.00/50 µg
QTY
For bulk pricing, please contact us.
Catalog Number : MM-0061-P
  • Product Name
    HRS Mouse Monoclonal Antibody - Purified
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Research Area(s)
    Cell Biology, Signal Transduction
  • Immunogen
    Full length hrs-2 fusion protein
  • Clone ID
    19-May
  • DataSHEET
  • Isotype
    IgG2b
  • Conjugation
    None
  • Reactivity
    The antibody recognizes an epitope is located between the VHS and coiled-coil domain of the HRS protein
  • Specificity
    Human, Mouse, Rat and Monkey
  • Purification
    Purified
  • Storage Buffer
    PBS
  • Format
    50 µg
  • Background
    Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS, also known as HGS) is a mammalian protein predominantly localized on early endosomes. Hrs interacts with many proteins involved in membrane trafficking, such as eps15, SNX-1 and SNAP-25. Hrs is implicated in early endosome fusion and may play a role in cargo sorting/trafficking to early and late endosome by recruiting clathrin. Hrs is also involved in intracellular signal transduction mediated by cytokines and growth factors.

For laboratory research only, not for drug, diagnostic or other use.

  • CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor
  • The endosome-associated protein Hrs is hexameric and controls cargo sorting as a "master molecule".
  • The cellular and developmental expression of hrs-2 in rat
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$333.00

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