HMG Co A reductase Rabbit Polyclonal Antibody | MédiMabs

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HMG Co A reductase Rabbit Polyclonal Antibody

HMG Co A reductase  Rabbit Polyclonal Antibody

  • HMG Co A reductase  Rabbit Polyclonal Antibody

HMG Co A reductase Rabbit Polyclonal Antibody

MM-0197 -- anti-HMG Co A reductase
$355.00/100 µl
QTY
For bulk pricing, please contact us.
Catalog Number : MM-0197
  • Product Name
    HMG Co A reductase Rabbit Polyclonal Antibody
  • Host
    Rabbit
  • Clonality
    Polyclonal
  • DataSHEET
  • Conjugation
    None
  • Reactivity
    Rat
  • Specificity
    Full length
  • Purification
    Non Purified
  • Format
    100 µl
  • Background
    HMG-CoA reductase (also known as 3-hydroxy-3-methyl-glutaryl-CoA reductase or HMGCR) is a transmembrane glycoprotein involved in the control of cholesterol biosynthesis. It is the rate-limiting enzyme of sterol biosynthesis; it is a ubiquitously expressed glycoprotein that is bound to the membrane of the endoplasmic reticulum. HMG-CoA reductase is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. HMG-CoA is inhibited by statin, a class of cholesterol-lowering drugs which lower plasma cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor.

For laboratory research only, not for drug, diagnostic or other use.

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