Munc13-4 Rabbit Polyclonal Antibody | MédiMabs

Munc13-4 Rabbit Polyclonal Antibody

Munc13-4 Rabbit Polyclonal Antibody

Munc13-4 Rabbit Polyclonal Antibody

MM-0130 -- anti-Munc13-4
$355.00/50 µl
For bulk pricing, please contact us.
Catalog Number : MM-0130
  • Product Name
    Munc13-4 Rabbit Polyclonal Antibody
  • Host
  • Clonality
  • Tested Applications
  • DataSHEET
  • Conjugation
  • Reactivity
  • Specificity
  • Purification
    Non Purified
  • Target Name
  • Alias
  • Format
    50 µl
  • Background
    Protein unc-13 homolog D (Munc13-4) is involved in cytotoxic granule exocytosis in lymphocytes. It regulates assembly of recycling and late endosomal structures which leads to the formation of an endosomal exocytic compartment. It also regulates Ca 2+-dependent secretory lysosome exocytosis in mast cells. Munc13- 4 is highly expressed in the spleen, thymus and leukocytes and to a lesser extent in the lung and placenta, brain, heart, skeletal muscle and kidney. Defects in Munc13-4 are the cause of hemophagocytic lymphohistiocytosis familial type 3 (FHL3).

For laboratory research only, not for drug, diagnostic or other use.

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