Glutamate Receptor 3B Mouse Monoclonal Antibody | MédiMabs

Glutamate Receptor 3B Mouse Monoclonal Antibody

Glutamate Receptor 3B Mouse Monoclonal Antibody

Glutamate Receptor 3B Mouse Monoclonal Antibody

MM-0028 -- anti-Glutamate GluR3B
$355.00/100 µg
For bulk pricing, please contact us.
Catalog Number : MM-0028
  • Product Name
    Glutamate Receptor 3B Mouse Monoclonal Antibody
  • Host
  • Clonality
  • Tested Applications
    Western Blot (WB), ELISA, Flow Cytometry (FC)
  • Research Area(s)
    Neuroscience, Signal Transduction
  • Immunogen
    GluR3-derived syntetic peptide GluR3B (aa372-395 of GluR3 with the sequence NEYERFVPFSDQQISNDSSSSENR
  • Modifications
  • Clone ID
  • DataSHEET
  • Isotype
  • Conjugation
  • Reactivity
    The antibody the extracellular domain of Glu3RB (aa 372 to 395)
  • Specificity
    Human, Rat, Pig
  • Purification
    Non Purified
  • Target Name
    Glutamate Receptor 3B
  • Storage Buffer
    Protein free tissue culture supernatant
  • Alias
    GluR-3 Glutamate receptor 3 AMPA-selective glutamate receptor 3 GluR-C GluR-K3 Glutamate receptor ionotropic, AMPA 3 GluA3
  • Format
    100 µg
  • Background
    Glutamate is the main excitatory neurotransmitter in the mammalian central nervous system (CNS). Its receptors are either metabotropic or ionotropic. The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor, also known as the AMPA receptor, is an ionotropic receptor made up of homomeric or heteromeric arrangements of Glutamate Receptor (GluR) subunits 1 to 4. GluR3 is one of the most common AMPA receptor in the CNS. The receptors are localized mainly post-synaptically and play important roles in the development and function of the nervous system. Autoimmunity to glutamate receptors may contribute to the pathology of some epilepsy syndromes.

For laboratory research only, not for drug, diagnostic or other use.

  • Autoantibodies against an extracellular peptide of the GluR3 subtype of AMPA receptors activate both homomeric and heteromeric AMPA receptor channels
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