Claudin-16 Mouse Monoclonal Antibody (4C10) | MédiMabs

Claudin-16 Mouse Monoclonal Antibody (4C10)

Claudin-16 Mouse Monoclonal Antibody (4C10)

Claudin-16 Mouse Monoclonal Antibody (4C10)

MM-0217 -- anti-CLDN16
$355.00/100 µg
QTY
For bulk pricing, please contact us.
Catalog Number : MM-0217
  • Product Name
    Claudin-16 Mouse Monoclonal Antibody (4C10)
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Tested Applications
    IF
  • Clone ID
    4C10
  • DataSHEET
  • Isotype
    IgM
  • Conjugation
    None
  • Reactivity
    Human
  • Specificity
    Full length
  • Target Name
    CLDN16
  • Format
    100 µg
  • Background
    Claudin-16 (CLDN-16) (also known as paracellin-1 (PCLN-1)), is an integral membrane protein and a component of tight junction strands. CLDN-16 has an important role in tight junction-specific elimination of the intracellular space through calcium-independent cell-adhesion activity. It is found in the apical region of polarized epithelial and endothelial cells but primarily in the kidneys, where it regulates the paracellular reabsorption of magnesium ions. Defects in the gene encoding CLDN-16 are the primary cause of Hypomagnesemia 3 (HOMG3) which is a progressive renal disease characterized by massive renal magnesium wasting. Recurrent urinary tract infection and kidney stones are current observed in patients with HOMG3.

For laboratory research only, not for drug, diagnostic or other use.

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$355.00

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