Chromogranin-A Rabbit Polyclonal Antibody | MédiMabs

Chromogranin-A Rabbit Polyclonal Antibody

Chromogranin-A Rabbit Polyclonal Antibody

Chromogranin-A Rabbit Polyclonal Antibody

MM-0179 -- anti-Chromogranin-A
$355.00/100 µl
QTY
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Catalog Number : MM-0179
  • Product Name
    Chromogranin-A Rabbit Polyclonal Antibody
  • Host
    Rabbit
  • Clonality
    Polyclonal
  • Tested Applications
    WB
  • Application Notes
    "Recommended starting dilutions: If reconstituted in 100 µl: WB: 1:1000 - 1:2000. Optimal dilution has to be determined by the user. "
  • Immunogen
    This antibody was raised against a region on the C-terminal of the human Chromogranin-A.
  • DataSHEET
  • Conjugation
    None
  • Reactivity
    Mammals
  • Specificity
    C-terminal
  • Purification
    Non Purified
  • Target Name
    Chromogranin A
  • Storage Buffer
    Lyophilized antibody
  • Alias
    anti-Chromogranin-A,anti-Pituitary secretory protein I,anti-SP-I
  • Format
    100 µl
  • Background
    Chromogranin-A is a secreted protein known as a “prohormone” which is found in endocrine cells and neurons and may be released upon stimulation. It is thought to be involved in the formation of dense core granules, where it may be processed to form the bioactive peptide serpinin, which is thought to regulate the biogenesis of dense core granules in endocrine cells. Chromogranin-A is used as a biomarker in patients with neuroendocrine tumours. Recent publications show that incomplete processing of Chromogranin-A may be linked to diabetic retinopathy.

For laboratory research only, not for drug, diagnostic or other use.

  • References
    "1. Fournier, I., et al. Processing of chromogranins/secretogranin in patients with diabetic retinopathy. Regulatory Peptides 167, 118-24. (2011)."
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$355.00

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