High-voltage calcium channels, beta-3 subunit Mouse Monoclonal Antibody (7D1) | MédiMabs

High-voltage calcium channels, beta-3 subunit Mouse Monoclonal Antibody (7D1)

High-voltage calcium channels, beta-3 subunit  Mouse Monoclonal Antibody (7D1)

High-voltage calcium channels, beta-3 subunit Mouse Monoclonal Antibody (7D1)

MM-0209 -- anti-High-voltage calcium channels, beta-3 subunit
$355.00/100 µg
QTY
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Catalog Number : MM-0209
  • Product Name
    High-voltage calcium channels, beta-3 subunit Mouse Monoclonal Antibody (7D1)
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Tested Applications
    ELISA, WB, IF
  • Clone ID
    7D1
  • DataSHEET
  • Isotype
    IgG1
  • Conjugation
    None
  • Reactivity
    Mouse
  • Specificity
    beta3 subunit
  • Purification
    Non Purified
  • Target Name
    High-voltage calcium channels
  • Format
    100 µg
  • Background
    Voltage-gated ion channels (VDIC) are a class of transmembrane ion channels that are activated by changes in electrical potential difference near the channel. Voltage-dependent calcium channels (VDCC) are multi-subunit membrane complexes that allow depolarization-induced calcium influx into cells. The opening and closing of these channels by depolarizing stimuli allows calcium ions to enter neurons producing transient intracellular Ca2+ signals. VDCCs are formed as a complex of several different subunits: alfa1, alfa2delta, beta1-4, and gamma. The alfa1 subunit forms the ion conducting pore. The beta subunit contributes to the function of the calcium channel. Specifically, the beta-3 subunit regulates activation and inactivation of the channels through phosphorylation. The beta-3 subunit is most prevalent in the brain but it can also be found in the lungs, heart, aorta, trachea and pancreatic islets.

For laboratory research only, not for drug, diagnostic or other use.

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$355.00

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